Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
ARTICLE
Year : 2009  |  Volume : 7  |  Issue : 14  |  Page : 55-59

Salivary J1-Glucuronidase as a marker for chronic Periodontitis


Department of Periodontics, Meenakshi Ammal Dental College, Chennai, India

Correspondence Address:
Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Aim: This study was conducted to correlate the relationship between J3-glucuronidase activity in whole saliva with severity of periodontal disease. Methodology: The study population consisted of 20 subjects (14 males and 6 females), selected from the out patient department of periodontics, Meenak:shi Ammal Dental College and Hospital, Chennai. A sample of unstimulated whole saliva and a venous blood sample were obtained from each subject, and a periodontal examination, which included measurement of pocket depth, attachment level, and gingival index was performed. The unmodified saliva samples were frozen at - 20°C and analyzed for -glucuronidase activity. The blood samples were analyzed for number of total leukocytes, neutrophils, lymphocytes and monocytes. Results: A significant positive relationship was found between increase J3-glucuronidase activity with increase pocket depth and attachment loss. In addition a significant correlation existed between neutrophil count and -glucuronidase activity. Conclusion: The results suggest that a significant association between periodontal clinical parameters and salivary J3-glucuronidase activity. Due to non-invasive and simple nature of saliva collection when compared to GCF, estimating the level of the enzyme, -glucuronidase in whole saliva might be used as a marker to assess the severity of periodontitis, and a means of monitoring the response to treatment.


[PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed963    
    Printed26    
    Emailed0    
    PDF Downloaded66    
    Comments [Add]    

Recommend this journal