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ARTICLE
Year : 2011  |  Volume : 9  |  Issue : 18  |  Page : 384-388

Fluoride biomarkers - A review (Part - I)


1 Senior Lecturer, Dept. of Public Health Dentistry, K. M. Shah Dental College and Hospital, Vadodara, Gujarat, India
2 Reader, Dept. of Public Health Dentistry, R.V.S Dental College and Hospital, Coimbatore, Tamil Nadu, India
3 Senior Lecturer, Dept. of Pedodontics and Preventive Dentistry, K. M. Shah Dental College and Hospital, Vadodara, Gujarat, India
4 Senior Lecturer, Dept. of Pedodontics and Preventive Dentistry, M.P. Patel Dental College and Hospital, Vadodara, Gujarat, India
5 Senior Lecturer, Dept. of Oral and Maxillofacial Pathology, K. M. Shah Dental College and Hospital, Vadodara, Gujarat, India

Correspondence Address:
Shilpa Gunjal
Senior Lecturer, Dept. of Public Health Dentistry, K. M. Shah Dental College and Hospital, Vadodara, Gujarat
India
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Source of Support: None, Conflict of Interest: None


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A biomarker is in general a substance used as an indicator of a biological state. The term biomarkerhas entered the epidemiological and environmental vocabulary as a short form for biological marker orbiochemical marker. It is a characteristic that can be objectively measured and evaluated as an indicatorof normal biological processes, pathogenic processes, or pharmacologic responses to a therapeuticintervention. A biomarker can also be used to indicate exposure to various environmental substances inepidemiology and toxicology.Fluoride is believed to be a major factor in the substantial decline in dental caries in the permanentdentition in many countries over the last several decades. It is also associated with dental fluorosis andhas potential health risks such as bone fragility if consumed in excessive amounts. A fluoride biomarkercan provide a cumulative record of exposures from birth and provide valid and reliable estimates of fluorideexposure amounts.


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