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ARTICLE
Year : 2011  |  Volume : 9  |  Issue : 5  |  Page : 341-346

Efficacy of three herbal extracts against three common Oral Microbes in comparison to Chlorhexidine: An invitro Study


1 Department of Community Dentistry, College of Dental Sciences, Davangere. Karnataka-577 004, India
2 Department of Pharmacognosy, Shree Dhanvantary Pharmacy College, Near Railway Station, Kim- 394 110, Surat District, Gujarat, India

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Background: The field of alternative medicine has seen a tremendous growth over the past few years. The interest in plants with antibacterial and anti-inflammatory activity has increased as a consequence of current problems associated with the wide-scale misuse of antibiotics that induced microbial drug resistance. Objective: 1.To evaluate effect of herbal extracts of Azadirachta indica, Punica granatum and Acacia nilotica against common oral microbes. 2. To compare effect of herbal extracts of Azadirachta indica, Punica granatum and Acacia nilotica against common oral microbes with chlorhexidine. 3. To assess the minimal inhibitory concentrations of stevioside extracts against the three organisms. Methodology: The P. granatumpeel was separated, dried and powdered. A. nilotica bark obtained from the tree was powdered. A. indica leaves obtained from the tree were dried and powdered. Solvent extracts were prepared using Soxhlet apparatus. Antimicrobial activity was tested using agar ditch plate method. Zone of inhibition on all four sides was measured in millimeters with vernier caliper after 48 hours. One way Analysis of Variance (ANOVA) test was used for multiple group comparisons followed by Tukey post hoc for group wise comparisons. p-value 0.05 was considered statistically significant. Results: All three herbal extracts showed antimicrobial properties against the tested micro oraganisms. The maximum antimicrobial activity was shown by A. nilotica extract. Conclusion: Results showed that these herbs can be used as antiplaque agents as they are cheap and easily available. In vivo studies are needed to prove or refute their efficacy and safety in real environmental circumstances.


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