Source of Support: None, Conflict of Interest: None
Objectives: To study the effect of Salvadora persica (Miswak) and Mangifera indica (Mango) extracts on Streptococcus mutans and salivary pH and to compare between the two extracts.
Design: A double-blind cross-over study.
Participants: Twenty students (ages between 20-25 years) who volunteered to participate in the study were included.
Method: Participants were randomly divided into two groups. Each group was allocated for one of the extracts being tested. Subjects were instructed to rinse with the prepared extract for two minutes. Salivary samples were collected at baseline (pre-rinse), 10 and 60 minutes (post-rinse). After a washout period of one week, the study was repeated with participants rinsing with alternative extracts.
Main outcome measures: Salivary pH of the collected samples was measured. Microbiological analysis was performed for Streptococcus mutans.
Results: Microbial reduction was seen in 85% of the participants after rinsing with Salvadora persica and in 65% of the participants after rinsing with Mangifera indica extracts. Compared with the baseline value, both the extracts showed a significant increase in salivary pH (p < 0.000).