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Year : 2014  |  Volume : 12  |  Issue : 3  |  Page : 157-162

Efficacy of mouth rinses on dental plaque and gingivitis: A randomized, double-blind, placebo-controlled clinical trial

1 Department of Public Health Dentistry, Meghna Institute of Dental Sciences, Nizamabad, Telangana, India
2 Department of Public Health Dentistry, KVG Dental College and Hospital, Sullia, Karnataka, India

Correspondence Address:
Arun Shyam
Department of Public Health Dentistry, Meghna Institute of Dental Sciences, Nizamabad 503 003, Telangana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2319-5932.144785

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Introduction: Over the years chlorhexidine (CHX), triclosan and sodium fluoride (NaF) mouth rinses are used alone or combined in the prevention of dental diseases. However, at present little is known about the combined effects of NaF + triclosan and CHX + NaF + triclosan mouth rinses on reducing dental plaque and gingivitis. Aim: The aim was to determine the efficacy of mouth rinses used as adjuncts to regular oral hygiene measures on reducing dental plaque and gingivitis. Materials and Methods: A randomized, placebo-controlled, double-blind, parallel-group study was conducted for 6-month, among 12-15 years old school children in Nellore, India. Eligible subjects (n = 210) with consent were randomly allocated to four groups and were provided with a mouth rinse (Group A = 0.2% CHX; Group B = 0.05% sodium fluoride + 0.03% triclosan; Group C = 0.2% CHX + 0.05% sodium fluoride + 0.03% triclosan; Group D = Placebo). All subjects used 10 ml of mouth rinse, once daily for 60 s. The clinical parameters evaluated were plaque index (PlI) and gingival Index (GI). Statistical significance within and between four groups was tested using one-way analysis of variance (ANOVA), repeated measures ANOVA with post-hoc and paired t-test. Results: At the end of clinical trial, the three test groups showed statistically significant (P < 0.001) reduction in PlI and GI scores compared with placebo group. Conclusion: The active agents demonstrated highly potent antiplaque and antigingivitis properties when compared to placebo.

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