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ORIGINAL ARTICLE
Year : 2015  |  Volume : 13  |  Issue : 4  |  Page : 517-520

Antimicrobial effectiveness of Neem (Azadirachta indica) and Babool (Acacia nilotica) on Streptococcus mutans: An in vitro study


Department of Public Health Dentistry, A. J. Institute of Dental Sciences, Mangalore, Karnataka, India

Correspondence Address:
R Pandya Sajankumar
Department of Public Health Dentistry, A. J. Institute of Dental Sciences, NH 17, Kuntikhana, Mangalore - 575 004, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2319-5932.171159

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Introduction: There is an exponential growth in the field of herbal medicine because of their natural origin, easy availability, efficacy, and safety. Aim: To compare the antimicrobial effectiveness of Neem and Babool on Streptococcus mutans. Materials and Methods: An in vitro study was conducted to compare the effectiveness of 5%, 10%, and 50% of Neem and Babool aqueous extract with 5%, 10%, and 50% of 0.2% chlorhexidine mouthwash on S. mutans. The ditch plate method was used to test the antimicrobial activity. Ditches were prepared on blood agar plates with the help of punch having 7 mm diameter. The plates were left for 1 h at room temperature and then incubated at 37°C for 48 h and examined for zone of inhibition. Results: Inhibitory effect of 5% Neem is significantly better than 5% Babool and 5% chlorhexidine mouthwash (P < 0.05). At 10% and 50%, Neem and Babool are significantly better than chlorhexidine mouthwash (P < 0.05). Inhibitory effect of Babool increases as the concentration increases (P < 0.05). The inhibitory effect of 5% and 50% chlorhexidine mouthwash is better than 10% chlorhexidine mouthwash (P < 0.05). Conclusion: Aqueous extract of Neem exhibited the highest antimicrobial activity compared with Babool and chlorhexidine mouthwash.


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